Also referred to as blue or Maltese, grey is a common coat colour in both purebred and domestic cats. Grey is the dilute form of black, caused by the aptly named dilution gene which is caused by a single base deletion 1 bp in the melanophilin (MLPH) gene. This gene provides instructions for making melanophilin, a carrier protein that is found in pigment-producing melanocytes. Melanophilin is essential for the even distribution, transport, and translocation of melanin (pigment granules). Menalocytes are specialised cells that contain organelles known as melanosomes. Melanosomes synthesise, store and transport melanin out of the cell via the dendrites to neighbouring keratinocytes (keratin producing cells).
What is white spotting? White spotting (WS) is the appearance of areas of white on a solid or tabby cat and occurs in both purebred and random-bred cats. The gene responsible is dominant, which means the cat only needs to inherit one copy for white spotting to occur. The white spotting pattern is due to … Read more