Is Dettol toxic to cats?Â
Dettol is toxic to cats, the active ingredient is chloroxylenol, a phenol that is a common ingredient in antiseptics, creosote, germicides, cleaners, and disinfectants. Phenols are locally corrosive and cause necrosis of the skin, mucous membranes, and esophagus, central nervous system stimulant and depressant, kidney and liver damage.
The major sites of metabolism are the gastrointestinal tract, lungs, liver and kidneys. Cats lack UDP-glucuronosyltransferase (UGT) enzymes, including UGT1A6 and UGT1A9 necessary to metabolize phenols. Their accumulation in the liver and kidneys results in liver damage and renal tubular necrosis.